IBM and AMD Partner with Zyphra on Next Generation AI Infrastructure

IBM and AMD are collaborating to deliver advanced AI infrastructure to Zyphra, an open-source AI research and product company based in San Francisco, California.

Under a multi-year agreement between IBM and Zyphra, IBM is positioned to deliver a large cluster of AMD Instinct MI300X GPUs on IBM Cloud for Zyphra to use for training frontier multimodal foundation models.

This collaboration is expected to deliver among the largest advanced generative AI training capabilities to date powered by an AMD stack running on IBM Cloud, according to IBM.

Zyphra recently closed a Series A financing round at a $1B valuation to build a leading open-source/open-science superintelligence lab focused on advancing fundamental innovations in novel neural network architectures, long-term memory, and continual learning.

Zyphra partnered with IBM and AMD for their cutting-edge product roadmaps and ability to deliver GPU accelerators at the rapid pace required to drive Zyphra's innovation forward.

This agreement is the first large-scale, dedicated training cluster on IBM Cloud leveraging AMD Instinct MI300X GPUs and AMD Pensando Pollara 400 AI NICs and AMD Pensando Ortano DPUs. The initial deployment was made available to Zyphra in early September with planned expansion in 2026.

Zyphra will use the advanced training cluster to develop multimodal foundation models across language, vision and audio modalities to power Maia, a general purpose superagent designed to deliver productivity benefits for knowledge workers across enterprise.

IBM and AMD are uniquely positioned to continue scaling computational resources as Zyphra's AI model training needs expand.

"This collaboration marks the first time AMD's full-stack training platform—spanning compute through networking—has been successfully integrated and scaled on IBM Cloud, and Zyphra is honored to lead the way in developing frontier models with AMD silicon on IBM Cloud," said Krithik Puthalath, CEO and chairman of Zyphra. "We're excited to partner with IBM and AMD to power the next era of open-source, enterprise superintelligence."